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. 2021 Apr 22;13(9):2014. doi: 10.3390/cancers13092014

Table 5.

Sialyltransferases involved in angiogenesis.

STs Target/Mediator Effect Cancer Type References
ST3GAL1 Vasorin-TGFβ1 Promotion Breast cancer [100]
ST6GAL1 PECAM/VEGFR2/Intβ3 Promotion Lewis lung carcinoma [101]
ST6GAL1 VEGF Promotion Osteosarcoma [102]
ST6GAL1 HIF-1α Promotion Ovarian, pancreatic cancers [104]
ST8SIA1 EGF/VEGF Inhibition Pancreatic cancer [107]