Table 6.
Sialyltransferases involved in chemoresistance.
| STs | Target/Mediator | Effect | Cancer Type | References |
|---|---|---|---|---|
| ST3GAL1 | Promotion | ER+ breast cancer | [41] | |
| ST3GAL1 | Promotion | Ovarian cancer | [57] | |
| ST3GAL1 | Promotion | CML | [114] | |
| ST3GAL4/6 | Promotion | Gastric adenocarcinoma | [116] | |
| ST6GAL1 | EGFR | Promotion | Colon, ovarian cancers | [108,109] |
| ST6GAL1 | FGFR1 | Promotion | Ovarian cancer | [69] |
| ST6GAL1 | HER2-AKT-ERK | Promotion | Gastric cancer | [111] |
| ST6GALNAC1 | sTn | Promotion | Gastric cancer | [119] |
| ST6GALNAC2 | Promotion | Colorectal cancer | [120] | |
| ST8SIA4 | P-gp/MRP1 | Promotion | AML | [117] |