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Targets for “Group 3” drugs with selective effect in each cell line.
| G18-T Cells | FPW1 Cells | ||
|---|---|---|---|
| Drug Name | Target | Drug Name | Target |
| Pazopanib | c-kit, PDGFR, VEGFR | AZD5363 | Akt |
| Disuliram | ALDH | Pexidartinib | CSF-1R, c-Kit |
| RITA | E3 ligase, p53 | Dafrafenib | Raf |
| Oroxin B | ER | S31-201 | STAT |
| 2-methoxyestradiol | GPR30 | Temozolomide | DNA damage |
| Vismodegib | Hh/GLI | ||
| Costunolide | hTERT | ||
| Trametinib | MEK | ||
| AZD8055 | mTOR | ||
| Partenolide | HDAC, IKK-β, NF-κB | ||
| Imatinib Mesylate | PDGFR | ||
| Omipalisib | PI3K/mTOR | ||
| WP1066 | Stat3 | ||
