Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The role of calcium/calmodulin-dependent kinase (CaMK) II and IV in antidepressant-like, anxiolytic-like, and procognitive effects. The procognitive effect requires activation of both CaMKII and CaMKIV. For antidepressant-like activity to be induced, CaMKIIα and CaMKIV need to be activated, and CaMKIIβ inactivated. The data on the anxiolytic-like effect depend on the studied brain region.
