Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 15;40:171. doi: 10.1186/s13046-021-01978-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 8 — The expression patterns of representative splicing events regulated by SRSF1 in vivo and the clinical significance of splicing switching of PTPMT1. a Splicing pattern of PTPMT1/SMARCD1/GAB1/TERF1 in breast cancer and their paired adjacent tissues (n = 6) as detected by RT-PCR. b Comparison of the PSI of PTPMT1/TERF1/SMARCD1 in the 113 cancer and matched normal tissues from TCGA dataset. c Kaplan-Meier analysis of the OS of the high- (low PSI of PTPMT1 and high expression of SRSF1) and low-risk (high PSI of PTPMT1 and low expression of SRSF1) group in stage I-II or stage III-IV cohort based on TCGA data. The median of PSI of PTPMT1 or mRNA expression of SRSF1 are used as the cutoff. d The model of how SRSF1 mediates BRCA progression through modulating AS