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Cytotoxicity was measured with the MTT assay after 48 h of treatment in T24 cells or gemcitabine-resistant T24 cells (T24-GCB) with serial concentrations of (A) gemcitabine (GCB) and (B) ellagic acid (EA). The cytotoxicity of the combined treatment of EA and GCB was also evaluated in (C) T24 and (D) T24-GCB cells. ** < 0.01 and *** < 0.001.
