Table 1.
Detailed histological measurements (infarction size, heart volume) and echocardiographic parameters (EF, FS, End-Diastolic Diameter, Heart rate, Cardiac output).
| Parameter | Control n = 6 |
PS n = 6 |
PS after n = 6 |
p |
|---|---|---|---|---|
| Infarct size (% from 3D reconstructed volume) |
12.15 ± 2.57 | 8.33 ± 2.56 $ | 7.95 ± 3.03 $ | * p = 0.0337 |
| Heart Volume (µm3) | 14.674 ± 2869 | 15.140 ± 1538 | 16.401 ± 2074 | p = 0.4037 |
| Ejection Fraction—EF (%) | 29.17 ± 4.44 | 38.50 ± 7.53 $ | 38.17 ± 5.07 $ | * p = 0.0225 |
| Fractional shortening—FS (%) | 19.28 ± 1.33 | 23.94 ± 1.13 $ | 23.05 ± 1.07 | * p = 0.0324 |
| Cardiac output (ml/min) | 10.34 ± 2.68 | 18.22 ± 3.94 $ | 18.65 ± 4.63 $ | * p = 0.0028 |
| End-Diastolic Diameter (mm) | 4.16 ± 0.22 | 3.83 ± 0.19 $ | 3.97 ± 0.21 | * p = 0.0500 |
| Heart rate (bpm) | 384 ± 27.72 | 381 ± 33.83 | 373 ± 36.36 | p = 0.8559 |
Values ± SD, $ significant difference vs Control, Phosphatidylserine (PS); Ejection Fraction (EF); Fractional shortening (FS), * significant difference.