Figure 1.

Application of the prognostic adaptive immune response signature developed by Qin et al. [60] to the TCGA-UM dataset. Euclidean hierarchical cluster Heatmap for 80 P-UM, highlighting mRNA expression levels of Qin et al. [60] immune signature genes. Responder genes are labeled in green, non-responder genes are labeled in blue. The expression values are reported by a color scale (blue = expression below the mean, red = expression above the mean, white = expression at the mean; the intensity is related to the distance from the mean). This signature shows three main clusters defined by differentially expressed profiles between responders versus non-responders genes.