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. 2021 Apr 23;10(9):1848. doi: 10.3390/jcm10091848

Table 2.

Characteristics of the main PET radiotracers.

Radiotracer Half-Life Advantages Disadvantages
15O-water 120 s -High myocardial extraction fraction -Limited application to facilities with an on-site
cyclotron
82Rubidium 76 s -Not requiring a cyclotron on site -Significant roll-off at high flows
-Low myocardial extraction fraction
13N-ammonia 10 min -High myocardial extraction fraction -Requiring a cyclotron on site
18F-labeled agents variable -Flow-independent high extraction fraction (>90%) -Alterations in the metabolic state of the myocardium may affect its retention
-Current use only in investigational trials