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. 2021 Apr 23;18(9):4506. doi: 10.3390/ijerph18094506

Table 2.

OSCC-related items explored in the questionnaire-based surveys.

Knowledge
1. Risk factors
Tobacco
Alcohol
Prior OSCC
Advanced age
HPV infection
Sun exposure
Diet
Betel quid chewing
Fungal infection
Immunosuppression
Radiotherapy
2. Non-risk factors
Family history
Familiar clustering
Ill-fitting prothesis
Hot food and drink
Poor oral hygiene
Use of spicy food
Obesity
3. OPMDs
Leukoplakia
Erythroplakia
Lichenoid lesions
Chronic hyperplastic candidiasis
Actinic cheilitis
Oral sub-mucous fibrosis
4. Common sites of development
Lip
Tongue
Floor of the mouth
Buccal mucosa
Palate
Gum
5. Clinical presentation
OSCC is the most common form of oral cancer
OSCC is asymptomatic at early stage
OSCC is diagnosticated more frequently at advanced stage
Lymph node characteristic of OSCC metastasis
Early OSCC lesions appear as small, painless red area
Ventral lateral border of the tongue most likely to develop OSCC
Submandibular lymph nodes are the first places of metastasis of OSCC
Lung is the most common site of distant metastasis of OSCC
Persistent ulcer, lump, non-healing socket, and/or bleeding gums could be signs of OSCC
Dysphagia
Limited tongue mobility
Attitude
Adequate/inadequate OSCC education received at medical/dental school
Quality of OSCC education
Up-to-date knowledge
Need to perform annual OSCC screening examinations for patients > 40 years old
Early detection improves 5-year survival rate
Training level in providing education on smoking cessation
Training level in OSCCC examination/screening
Believe/do not believe dentist/physician/dental hygienist is qualified to perform OSCC examination
Comfortable/uncomfortable during neck lymph nodes palpation
Comfortable/uncomfortable to refer suspicious oral lesions to specialists
Confident/non-confident in diagnosis of OSCC from clinical appearance
Patients’ knowledge level about risk factors
Should/should not inform patients about findings
Comfortable/uncomfortable to perform biopsy
Advise/do not advise patients with suspicious oral lesions
Need of continuous education in the future
Adequate/inadequate preparation to explain the risks of tobacco/alcohol use
Practice
Extra/intraoral examination
Lymph nodes palpation
Biopsy
Use of blue toluidine/fluorescent light
Asking about current/previous use of tobacco
Asking about the type and amounts of tobacco products used
Asking about current/previous use of alcohol
Asking about the type and amounts of alcohol use
Asking about personal/family history of cancer
Asking about type of diet
Asking about sun exposure
Refer to a specialist (as oral and maxillofacial surgeons, oral medicine specialists, ENT, physicians, specialized hospital)

Abbreviations: OSCC: Oral squamous cell carcinoma; ENT: Otolaryngologist.