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. 2021 Apr 23;22(9):4439. doi: 10.3390/ijms22094439

Figure 5.

Figure 5

The AMPK activator, AICAR, attenuates NMDA-induced cell loss in the ganglion cell layer (GCL). The number of cells in the GCL and thickness of the inner plexiform layer (IPL) were measured seven days after intravitreal injection. (A): Saline (a); NMDA (200 nmol) + vehicle (b); NMDA (200 nmol) + AICAR (20 nmol) (c); NMDA (200 nmol) + AICAR (50 nmol) (d). Scale bar, 30 µm. (B): Bar graph showing the number of cells in the GCL and thickness of the IPL. n = 5–6. ** p < 0.01; Kruskal–Wallis test.