Figure 4.

Rescue of embryonic lethality in C. elegans. Percentage of F0 adult worms able to give an F2 progeny. The number of F0 adult worms in 8 days treated with RNAi ant1-1 in the presence of otilonium bromide (OTI) or pergolide mesylate (PER) giving an F2 progeny (blue bars) was compared to that obtained without the addition of the drugs (red bar), where, instead, the same amount of DMSO (compound vehicle) was added. Statistical analysis was performed using Wilcoxon test comparing treated (blue bars) versus untreated mutant (red bar): ** p < 0.05; *** p < 0.001.