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. 2021 May 12;9:e11388. doi: 10.7717/peerj.11388

Figure 4. Neurite outgrowth and the number of neuronal cells from hNPCs-derived neurons response to BDNF treatment.

Figure 4

(A) The total neurite length of both cell lines significantly increased when incubated with BDNF (5 and 20 ng/ml). (B) Total neurite length per cell of Ctrl1 significantly decreased following BDNF treatment (5 and 20 ng/ml), while there was no significant difference in total neurite length per cell in fAD1 after treated with BDNF (5 and 20 ng/ml). (C) Number of neuronal cells of Ctrl1 significantly increased when incubated with BDNF (5 and 20 ng/ml). (D) Number of neuronal cells of fAD1 significantly increased when incubated with BDNF (5 and 20 ng/ml). Data are represented as mean ± SEM of three independent experiments. *p ≤ 0.05 and **p ≤ 0.01 vs. values obtained in the control group (0 ng/ml BDNF); ##p ≤ 0.01 vs. fAD1, by one-way ANOVA followed by Tukey’s test.