Table 1.
Comparison of clinical variables and hypoperfusion intensity ratio between patients with and without favorable outcome.
| Variables | All Patients (n = 162) |
Favorable Outcome (n = 85) |
Unfavorable Outcome (n = 77) |
p-Value |
|---|---|---|---|---|
| Age | 70.7 (± 12.8) | 67.6 (± 12.9) | 74.1 (± 11.8) | 0.001 |
| Sex, male | 84 (51.9) | 48 (56.5) | 36 (46.8) | 0.216 |
| Hypertension | 122 (75.3) | 65 (76.5) | 57 (74.0) | 0.719 |
| Diabetes | 75 (46.3) | 31 (36.5) | 44 (57.1) | 0.008 |
| Hypercholesterolemia | 77 (47.5) | 39 (45.9) | 38 (49.4) | 0.659 |
| Smoking | 31 (19.1) | 21 (24.7) | 10 (13.0) | 0.058 |
| Coronary artery disease | 29 (17.9) | 19 (22.4) | 11 (14.3) | 0.187 |
| Atrial fibrillation | 80 (49.4) | 38 (44.7) | 42 (54.5) | 0.211 |
| Occlusion site | 0.406 | |||
| Internal carotid artery | 64 (39.5) | 31 (36.5) | 33 (42.9) | |
| Middle cerebral artery | 98 (60.5) | 54 (63.5) | 44 (57.1) | |
| Initial NIHSS score | 15.0 [11.0; 19.8] | 12.0 [7.0; 16.0] | 19.0 [15.0; 20.0] | <0.001 |
| Use of intravenous tPA | 78 (48.1) | 50 (58.8) | 28 (36.4) | 0.004 |
| ASPECTS | 7.0 [5.0; 9.0] | 8.0 [7.0; 9.0] | 6.0 [4.0; 7.0] | <0.001 |
| Onset-to-recanalization, min | 298.5 [197.0; 583.5] | 274.0 [190.0; 434.0] | 336.0 [212.0; 674.0] | 0.045 |
| Symptomatic ICH | 10 (6.2) | 4 (4.7) | 6 (7.8) | 0.520 |
| Volume of rCBF < 30% (mm3) | 33.7 (± 53.6) | 12.0 (± 21.7) | 57.6 (± 66.7) | <0.001 |
| Volume of Tmax > 6 s (mm3) | 160.8 (± 76.7) | 140.4 (± 67.6) | 183.2 (± 80.2) | <0.001 |
| Hypoperfusion intensity ratio | 0.51 [0.29; 0.68] | 0.45 [0.15; 0.54] | 0.60 [0.44; 0.73] | <0.001 |
Values in parentheses represent the standard deviation (±) or number of patients (%); brackets represent first and third quartiles, respectively. NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator; ASPECTS, Alberta Stroke Program Early Computed Tomography Score; ICH, intracerebral hemorrhage; rCBF, relative cerebral blood flow.