Table 4.
Comparison of the Rate of Evolution Toward Severe COVID-19 According to the HOME-CoV Rule and According to Patient Management (Adjusted Population)
| HOME-CoV Rule Findings | Management | Observational Period |
Interventional Period |
Comparison: Absolute Difference (95% CI) | ||
|---|---|---|---|---|---|---|
| No. of Patients | % | No. of Patients | % | |||
| Patient management | ||||||
| Positive | Home treatment | 374/1,243 | 30.1 | 296/1,235 | 24 | –6.1% (–9.5% to –2.6%) |
| Hospitalization | 320/1,243 | 25.7 | 312/1,235 | 25.26 | –0.4% (–3.9% to 3.0%) | |
| Negative | Home treatment | 474/1,243 | 38.1 | 560/1,235 | 45.3 | +7.2% (3.3%-11.1%) |
| Hospitalization | 75/1,243 | 6.0 | 67/1,235 | 5.4 | –0.6% (–1.2% to 2.5%) | |
| Evolution toward severe COVID-19a | ||||||
| Positive | Home treatment | 1/374 | 0.3 | 1/296 | 0.3 | 0 |
| Hospitalization | 31/320 | 9.8 | 17/312 | 5.4 | –4.4% (–5.7% to –2.4%) | |
| Negative | Home treatment | 0/474 | 0 | 0/560 | 0 | 0 |
| Hospitalization | 3/75 | 3.4 | 1/67 | 1.5 | –1.9% (–3.2% to –0.8%) | |
HOME-CoV = Hospitalization or Outpatient Management of Patients With SARS-CoV-2 Infection.
a
Severe COVID-19 was defined as cases in which patients were either undergoing mechanical ventilation or dead.