Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 26;13(9):2085. doi: 10.3390/cancers13092085

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Speculative model of FOXA interaction with estrogen and androgen receptor in healthy and diseased liver. This schematic representation illustrates the potential interaction of FOXA transcription factors with both wild-type estrogen (ERα66) and androgen (AR) receptors, respectively in the prevention or promotion of liver diseases, including HCC. The hypothetical role of the ERα36 splice variant in the abrogation of ER/FOXA-mediated estrogen protective effects is also highlighted (modified and adapted from [88]).