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. 2021 Apr 26;26(9):2535. doi: 10.3390/molecules26092535

Scheme 1.

Scheme 1

Concentration of a drug (blue; axis Y) during the period of treatment (axis X) must be in a range of effective treatment level of a drug (area marked in green), whereas it must never be in the range of levels of a drug, which is toxic (area marked in red) and should not be in the range of therapeutically ineffective level of a drug (area marked in yellow) in the site of the drug action. The time interval between two consecutive applications is indicated—i.