Table 1.
Weights and ischemic contracture.
| n | Body Weight (g) |
Heart Weight Wet (g) |
Heart Weight Dry (g) |
Time of Max. Ischemic Contracture (min) |
Level of Max. Ischemic Contracture (mmHg) | ||
|---|---|---|---|---|---|---|---|
| Part 1 | |||||||
| HG | Con | 7 | 298 ± 8 | 1.21 ± 0.10 | 0.13 ± 0.01 | 14 ± 1 | 85 ± 11 |
| Lev0.3 | 7 | 312 ± 7 | 1.22 ± 0.07 | 0.14 ± 0.01 | 15 ± 2 | 82 ± 9 | |
| Lev1 | 7 | 311 ± 14 | 1.28 ± 0.08 | 0.14 ± 0.01 | 15 ± 1 | 75 ± 11 | |
| Lev3 | 7 | 313 ± 17 | 1.32 ± 0.07 | 0.14 ± 0.02 | 15 ± 1 | 82 ± 10 | |
| Lev10 | 7 | 308 ± 13 | 1.22 ± 0.05 | 0.14 ± 0.02 | 16 ± 1 | 65 ± 8 * | |
| Part 2 | |||||||
| HG | Con | 5 | 316 ± 11 | 1.27 ± 0.04 | 0.14 ± 0.00 | 16 ± 2 | 75 ± 15 |
| Lev0.3 | 5 | 288 ± 21 | 1.24 ± 0.07 | 0.12 ± 0.01 | 15 ± 2 | 79 ± 10 | |
| CsA | 5 | 294 ± 24 | 1.15 ± 0.08 | 0.12 ± 0.01 | 15 ± 2 | 77 ± 7 | |
| Lev0.3+CsA | 5 | 307 ± 11 | 1.19 ± 0.04 | 0.12 ± 0.01 | 15 ± 2 | 68 ± 8 | |
Data are mean ± SD, HG = Hyperglycemia; Con = Control; Lev = Levosimendan; CsA = Cyclosporine A (mPTP inhibitor); * p < 0.05 vs. Con.