Table 2.
Baseline | Reperfusion | ||||
---|---|---|---|---|---|
30 | 45 | 60 | |||
Heart Rate (bpm) | |||||
HG | Con | 316 ± 43 | 242 ± 41 | 219 ± 57 | 207 ± 69 |
Lev0.3 | 307 ± 36 | 255 ± 32 | 228 ± 52 | 267 ± 43 | |
Lev1 | 288 ± 38 | 263 ± 109 | 271 ± 83 | 292 ± 40 | |
Lev3 | 278 ± 20 | 231 ± 48 | 208 ± 65 | 214 ± 45 | |
Lev10 | 282 ± 20 | 222 ± 64 | 248 ± 86 | 239 ± 79 | |
Left Ventricular Developed Pressure (mmHg) | |||||
HG | Con | 109 ± 9 | 27 ± 11 * | 35 ± 12 * | 33 ± 6 * |
Lev0.3 | 107 ± 16 | 22 ± 14 * | 25 ± 9 * | 21 ± 10 * | |
Lev1 | 117 ± 17 | 13 ± 10 * | 20 ± 9 * | 20 ± 11 * | |
Lev3 | 114 ± 13 | 12 ± 12 * | 20 ± 14 * | 26 ± 7 * | |
Lev10 | 122 ± 11 | 12 ± 10 * | 19 ± 9 * | 25 ± 10 * | |
Coronary flow (mL/min) | |||||
HG | Con | 12 ± 2 | 6 ± 1 * | 6 ± 1 * | 6 ± 1 * |
Lev0.3 | 12 ± 3 | 6 ± 1 * | 6 ± 1 * | 6 ± 1 * | |
Lev1 | 13 ± 2 | 6 ± 1 * | 6 ± 1 * | 6 ± 1 * | |
Lev3 | 13 ± 2 | 6 ± 2 * | 7 ± 2 * | 6 ± 2 * | |
Lev10 | 14 ± 3 | 8 ± 3 * | 8 ± 3 * | 8 ± 3 * |
Data are mean ± SD. HG = Hyperglycemia; Con = Control; Lev = Levosimendan; * p < 0.05 vs. Baseline.