Table 4.
Baseline | Pre Ischemia |
Reperfusion 15 |
Reperfusion 60 |
||
---|---|---|---|---|---|
Part 1 | |||||
HG | Con | 196 ± 5 | 370 ± 10 * | 394 ± 18 * | 425 ± 44 * |
Lev0.3 | 197 ± 6 | 374 ± 37 * | 393 ± 11 * | 425 ± 28 * | |
Lev1 | 197 ± 2 | 360 ± 46 * | 389 ± 13 * | 409 ± 33 * | |
Lev3 | 197 ± 4 | 377 ± 10 * | 389 ± 32 * | 393 ± 41 * | |
Lev10 | 198 ± 3 | 372 ± 16 * | 377 ± 13 * | 400 ± 32 * | |
Part 2 | |||||
HG | Con | 203 ± 3 | 384 ± 6 * | 389 ± 12 * | 418 ± 35 * |
Lev0.3 | 199 ± 9 | 373 ± 16 * | 391 ± 9 * | 441 ± 18 * | |
CsA | 204 ± 10 | 377 ± 9 * | 390 ± 10 * | 425 ± 20 * | |
Lev0.3 + CsA | 203 ± 6 | 389 ± 8 * | 398 ± 5 * | 448 ± 35 * |
Data are mean ± SD. HG = Hyperglycemia; Con = Control; Lev = Levosimendan; CsA = Cyclosporine A (mPTP inhibitor); * p < 0.05 vs. Baseline.