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. 2021 Apr 26;22(9):4534. doi: 10.3390/ijms22094534
AAV Adeno-associated virus
ADRP Autosomal dominant Retinitis Pigmentosa
CEP290 Ciliopathy gene centrosomal protein 290
CHM Choroideremia
CRISPR Clustered regularly interspaced short palindromic repeats
DSB Double strand break
GPCR G-protein coupled receptor
gRNA Guide RNA
HDR Homology-directed repair
IRBP Interphotoreceptor retinoid-binding protein
IRDs Inherited Retinal Dystrophies
IVT Intravitreal injection
LCA Leber’s Congenital Amaurosis
LRAT Lecithin retinol acyltransferase
MMEJ Microhomology-mediated end joining
NHEJ Non-homologous end joining
Nrl Neural retina-specific leucine zipper protein
RHO Rhodopsin
RP Retinitis Pigmentosa
RPE Retinal pigment epithelium
rAAV Recombinant Adeno-associated virus
O.S. Outer segments
PAM Protospacer adjacent motif
XLRs X-linked juvenile retinoschisis