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. 2021 Apr 27;22(9):4557. doi: 10.3390/ijms22094557
AE adverse event
AI-DILI autoimmune DILI
AIH autoimmune hepatitis
ANA antinuclear antigen
APC antigen-presenting cell
APAP acetaminophen
ATP adenosine triphosphate
CD cluster of differentiation
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DAMP damage-associated molecular pattern
DC dendritic cell
DILI drug-induced liver injury
FasL Fas ligand
GSH glutathione
GWAS genome-wide association studies
HLA human leukocyte antigen
HMGB1 high mobility group box-1
ICAM intercellular adhesion molecule
ICI immune checkpoint inhibitor
IFN-γ interferon gamma
iDILI idiosyncratic drug-induced liver injury
IL interleukin
iNKT invariant NKT cell
K18 keratin 18
KC Kupffer cell
LN lymph node
LPS lipopolysaccharide
MHC major histocompatibility complex
MMP metalloproteinase
NKT natural killer T cell
NLR NOD-like receptor
NO nitric oxide
PAMP pathogen-associated molecular pattern
PD-1 programmed cell death protein 1
PD-L1 programmed cell death ligand 1
PRS polygenic risk score
PTPN22 lymphoid-specific protein tyrosine phosphatase non-receptor type 22
RLR RIG-like receptor
ROS reactive oxygen species
SMA smooth muscle antigen
SNP single nucleotide polymorphism
SOD superoxide dismutase
TCR T cell receptor
Th T helper cell
TLR Toll-like receptor
TNF-α tumor necrosis factor alpha
TRAIL TNF-related apoptosis-inducing ligand
Treg regulatory T cell
VCAM vascular cell adhesion molecule
VEGF vascular endothelial growth factor