Table 1.
Postoperative outcomes after curative surgery for esophageal cancer in EP vs. YP.
| Author, Year [Reference] |
EP Definition(Years) |
No of EP Patients (% to All) |
Anastomotic Leakage (%) EP/YP |
Pulmonary Complications (%) EP/YP |
Cardiovascular Complications (%) EP/YP | Postoperative Mortality (%) EP/YP | |
|---|---|---|---|---|---|---|---|
| Aoyama, 2020 [43] | 75 | 24 (24.5) | 37.5/33.7 | 33.3/27.5 | 12.6/6.1 | 4.2/0 * | 30-day |
| Song, 2020 [58] | 79 | 35 (3.5) | - | - | - | 5.8/5.7 * | 90-day |
| Chen, 2019 [44] | 70 | 142 (25.8) | 17.6/10 | 4.2/7.6 | - | 2.1/2.9 | In-hospital |
| Chen, 2019 [53] | 80 | 34 (21.7) | - | 29/27 | 3/2 | 5/2 * | 90-day |
| Kanda, 2019 [45] | 75 | 59 (15.8) | 4/3 | 20/16 | 12.5/7.5 | - | - |
| Baranov, 2019 [46] | 75 | 89 (24.9) | 19.1/17.1 | 62.9/62.2 | 24.7/14 * | 9/5 | 90-day |
| Klevebro, 2018 [47] | 75 | 62 (16.9) | 8.3/10.7 | 20/19.7 | 6.7/5.7 | 18.6/7.6 * | 90-day |
| Schlottmann, 2018 [48] | 70 | 1544 (29.5) | - | 25/20 * | 9/4 * | 8.9/4.3 * | In-hospital |
| Paulus, 2017 [36] | 80 | 33 (50) | 18/12 | 18/6 | 24/21 | 18/9 | 90-day |
| Miyata, 2015 [49] | 70 | 213 (30) | - | 17/14 | - | 0/0.4 | In-hospital |
| Liu, 2015 [50] | 70 | 39 (21) | - | 30.8/6.8 * (♯) | 7.7/3.4 | - | |
| Stahl, 2014 [56] | 80 | 289 (-) | - | - | - | 8/2.1 * | - |
| Morita, 2013 [51] | 80 | 104 (10) | - | 13/17.7 | - | 13/4.8 | In-hospital |
| Mirza, 2013 [59] | 70 | 46 (22) | - | - | - | 11/9 | 30-day |
| Schweigert, 2013 [37] | 75 | 45 (15) | 13/13 | 53/30 * | - | 24/9 * | In-hospital |
| Tapias, 2013 [38] | 80 | 16 (3.4) | 0/4.8 | 31.3/10.8 * | 37.5/14.4 * | - | - |
| Markar, 2013 [52] | 80 | 32 (6.4) | - | 18.8/8.3 * | 31.3/16.7 * | 0/0.6 | 90-day |
| Cijs, 2010 [29] | 70 | 564 (29) | - | - | - | 11/5.4 * | In-hospital |
| Elsayed, 2010 [39] | 70 | 108 (33.1) | 5/9 | 32.5/37 | - | 12/5 * | In-hospital |
| Yang, 2010 [40] | 70 | 136 (50) | 6.6/4.4 | 17.6/8.1 * | 24.2/14 * | 5.9/0.7 * | - |
| Pultrum, 2010 [41] | 70 | 64 (27.4) | 13/18 | 56/42 | 36/16 * | - | - |
| Davies, 2010 [14] | 70 | 59 (21) | 5/6 | - | 3.4/1.4 | 7/2.4 | - |
| Alibakshi, 2009 [42] | 70 | 165 (34.4) | 7.2/7.9 | 10.3/9.8 | 6/4.4 | 3/2.8 | In-hospital |
| Takagawa, 2008 [25] | 75 | 19 (8.6) | - | - | - | 15.8/3 * | In-hospital |
| Morita, 2008 [57] | 80 | 16 (2.4) | - | - | - | 6/2 * | In-hospital |
| Ruol, 2007 [30] | 70 | 159 (21.5) | 7.5/10.2 | 17/15.3 | - | 1.9/2.7 | In-hospital |
| Finlayson, 2007 [54] | 80 | 3150 (11.3) | - | - | - | 19.9/8.8 * | In-hospital |
| Moskovitz, 2006 [32] | 80 | 31 (3.6) | 6.5/8.8 | 9.7/4.7 | 0/0.8 | 19.4/7.3 * | In-hospital |
| Ma, 2006 [33] | 70 | 60 (3.3) | 3.3/2 | 43.4/28.1 * | 38.3/19.8 * | 3.3/1.1 | In-hospital |
| Di Martino, 2005 [55] | 70 | 51 (46.8) | - | - | - | 12.1/4.1 * | In-hospital |
| Rahamim, 2003 [34] | 70 | 199 (33.4) | 4.5/6.1 | 10.1/5.1 * | 15.6/7 * | 12.1/5 * | 30-day |
| Sabel, 2002 [18] | 70 | 147 (36) | - | - | 23/13 (♯♯)8/0 *(†) | 4/2 | In-hospital |
| Fang, 2001 [35] | 70 | 79 (17.9) | 26.6/35.1 | - | - | 7.6/3.3 | In-hospital |
| Kinugasa, 2001 [31] | 70 | 55 (26.9) | 18.2/12.8 | 45.5/19.5 * | 20/8.1 | 10.9/5.4 | 60-day |
| Johansson, 2000 [60] | 70 | 48 (40) | - | - | - | 0/2.8 | In-hospital |
EP = Elderly patients, YP = younger patients. Significant p-values < 0.05 are indicated with an asterisk *. (♯) Reported jointly as ‘cardiopulmonary morbidity’, (♯♯) rates of atrial fibrillation, (†) rates of infarctus.