Table 2.
Effects of cadmium and selenium on biochemical parameters after 30 days treatments 1.
| Biochemical Parameters | Group 1 (Control) |
Group 2 (Cd) |
Group 3 (Cd + 0.1SeNPs) |
Group 4 (Cd + 0.2SeNPs) |
Group 5 (Cd + 0.4SeNPs) |
Group 6 (Cd + 0.1LSeNPs) |
Group 7 (Cd + 0.2LSeNPs) |
Group 8 (Cd + 0.4LSeNPs) |
|---|---|---|---|---|---|---|---|---|
| AST (U/L) | 106.91 ± 16.50 | 142.62 ± 42.39 | 131.19 ± 42.44 | 74.71 ± 4.36 ### | 74.20 ± 12.19 ### | 79.09 ± 10.71 ### | 88.66 ± 30.46 ## | 78.60 ± 16.61 ### |
| ALT (U/L) | 57.15 ± 5.89 | 78.82 ± 14.17 | 72.32 ± 17.23 | 38.62 ± 8.42 ### | 35.74 ± 11.97 ### | 34.16 ± 7.73 *, ### | 35.53 ± 10.91 *, ### | 33.43 ± 7.16 *, ### |
| GGT (U/L) | 2.37 ± 0.31 | 2.62 ± 0.54 | 1.35 ± 0.71 *,## | 2.5 ± 0.10 | 2.35 ± 0.42 | 2.02 ± 0.63 | 2.40 ± 0.73 | 2.96 ± 0.23 |
| Total bilirubin (mg/dL) | 0.19 ± 0.11 | 0.15 ± 0.04 | 0.22 ± 0.07 | 0.22 ± 0.06 | 0.19 ± 0.07 | 0.16 ± 0.05 | 0.15 ± 0.04 | 0.099 ± 0.07 |
1 All values were expressed as the mean ± SD for 10 mice in each group. Groups: Cd + SeNPs and Cd + LSeNPs at different concentration vs. control group: * p < 0.05. Groups: Cd + SeNPs and Cd + LSeNPs at different concentration vs. cadmium group: ## p < 0.01; ### p < 0.001. Groups: 1—control; 2—CdCl2; 3—CdCl2 + 0.1 mg/kg SeNPs; 4—CdCl2 + 0.2 mg/kg SeNPs; 5—CdCl2 + 0.4 mg/kg SeNPs; 6—CdCl2 + 0.1 mg/kg LSeNPs; 7—CdCl2 + 0.2 mg/kg LSeNPs; 8—CdCl2 + 0.4 mg/kg LSeNPs. In the groups 2 to 8, orally CdCl2 at a dose of 5 mg/kg b.w. was administrated.