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. 2021 May 11;13:83–90. doi: 10.2147/CPAA.S297903

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© 2021 Masadeh et al.

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The cytotoxicity of combinations of metformin and tested antibiotics in VERO cell line expressed as cell viability percentage, A. Metformin + Doxycycline, B. Metformin + Levofloxacin, C. Metformin + Ampicillin, and D. Metformin + Rifampicin. Dose of combination is expressed as multiples of MIC of the combination of metformin and the tested antibiotic. Points between the two stars (*) are significantly different from baseline (zero dose) cell viability using unpaired t-test and P<0.05. Values are expressed as Mean±SD.