Table 1.

Baseline Characteristics of 46 Vitrectomized Eyes Receiving Aflibercept for DME

Number of eyes	46
Age (years), median, [Q1–Q3]	67.5 [59–73.5]
Gender M/F (%)	59/41
Type of diabetes (% type1/% type 2)	15/85
Duration of diabetes (years), median, [Q1–Q3]	17 [11.8–26.2]
HbA1c (%), median, [Q1–Q3]	7.6 [6.8–8.1]
Complications related to diabetes
Preexisting hypertension	33 (71.7%)
Cardiovascular disease	8 (17.4%)
Preexisting nephropathy	8 (17.4%)
Preexisting peripheral neuropathy	4 (8.7%)
Ocular history
Duration of DME (years), median, [Q1–Q3]	3 [0.5–5]
Time since vitrectomy, mean ± SD (y), median, [Q1–Q3] (m)	2 ± 4.4; 9 [3–24]
Reason for vitrectomy
Epiretinal membrane	27 (58.7%)
Vitreous hemorrhage	12 (26.1%)
Vitreomacular traction	4 (8.7%)
Retinal detachment	2 (4.3%)
Other	2 (4.3%)
Previous DME treatment	30 (65%)
Grid laser, n (%); mean number of treatment (min–max)	13 (43.3%); 2 (1–4)
Triamcinolone acetonide	8 (26.7%); 3(1–6)
Ranibizumab intravitreal injection	21 (70%); 7 (1–20)
Dexamethasone implant intravitreal injection	11 (36.7%); 1.5 (1–4)
Bevacizumab intravitreal injection	2 (6.7%), 1
Ocular characteristics
VA (ETDRS letter score), mean (SD); median, [Q1–Q3]	53.3 (14.7); 58.6 [45–65]
Phakic /Pseudophakic (%)	22.2/77.8
Intraocular pressure, (mmHg), median,[Q1–Q3]	16 [14–17]
DR severity on clinical examination
None	0
Microaneurysms only	2 (8%)
Mild/Moderate NPDR	16 (34.6%)
Severe NPDR	16 (34.6%)
PDR	10 (22.7%)
Previous scatter laser	25 (54.3%)
Macular ischemia on fluorescein angiography
Mild	13 (38.2%)
Moderate	14(41.2%)
Severe	7 (20.6%)

Abbreviations: M, male; F, female; DME, diabetic macular edema; ETDSR, Early Treatment Diabetic Retinopathy Study; DR, diabetic retinopathy; NPRD, non-proliferative diabetic retinopathy; PRD, proliferative diabetic retinopathy; VA, visual acuity; SD, standard deviation.