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. 2021 May 11;13:3789–3801. doi: 10.2147/CMAR.S290629

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© 2021 Fan et al.

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Circ_CORO1C acted as a sponge of miR-138-5p. (A) The binding sites between circ_CORO1C and miR-138-5p, as well as the mutant. (B and C) Dual-luciferase reporter assay for the luciferase intensity of circ_CORO1C-wt and circ_CORO1C-mut in HGC-27 and MKN45 cells transfected with miR-NC or miR-138-5p. (D) QRT-PCR assay for the relative expression of miR-138-5p in HGC-27 and MKN45 cells transfected with si-NC or si-circ_CORO1C. (E) QRT-PCR assay for the relative expression of miR-138-5p in GC tissues (n=50) and matched adjacent normal tissues. (F) Pearson correlation analysis for the correlation between expression of circ_CORO1C and miR-138-5p in GC tissues. (G) QRT-PCR assay for the relative expression of miR-138-5p in GES-1, HGC-27 and MKN45 cells. *P <0.05.