Table 2.
Anti-JCV Ab prevalence and antibody index by patients’ sex, disease course and EDSS score.
| n (%) | All | F | M | MW-U | RRMS | SPMS | PPMS | KW-H Post hoc |
EDSS I | EDSS II | EDSS III | KW-H Post hoc |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JCV+ | 924 (65.8) | 654 (66.1) | 270 (65.1) | p > 0.05 | 604 (63.2) | 183 (68.3) | 137 (75.3) | KW-H p = 0.005 RRMS-PPMS p = 0.03 Other p > 0.05 |
313 (60.9) |
343 (67.1) |
268 (70.5) |
KW-H p = 0.008 EDSS(1)-EDSS(3) p = 0.04 Other p > 0.05 |
| JCV− | 481 (34.2) | 336 (33.9) | 145 (34.9) | 351 (36.8) | 85 (31.7) | 45 (24.7) | 201 (39.1) |
168 (32.9) |
112 (29.5) |
|||
| AI Mean | 1.44 | 1.43 | 1.47 | p > 0.05 | 1.39 | 1.46 | 1.71 | KW-H p = 0.009 RRMS-PPMS p = 0.006 Other p > 0.05 |
1.35 | 1.46 | 1.55 | KW-H p = 0.06 |
| AI Median | 0.95 | 0.96 | 0.93 | 0.79 | 1.04 | 1.75 | 0.72 | 1.02 | 1.19 | |||
| AI Min | 0.03 | 0.03 | 0.09 | 0.03 | 0.09 | 0.09 | 0.06 | 0.03 | 0.07 | |||
| AI Max | 4.51 | 4.51 | 4.50 | 4.51 | 4.07 | 4.13 | 4.51 | 4.50 | 4.13 | |||
| AI SD | 1.29 | 1.28 | 1.32 | 1.29 | 1.29 | 1.28 | 1.29 | 1.29 | 1.29 |
F—female, M—male, RRMS—relapsing–remitting multiple sclerosis, SPMS—secondary progressive multiple sclerosis, PPMS—primary progressive multiple sclerosis, EDSS I—from 0 to 2.0, EDSS II—from 2.5 to 4.5, EDSS III—from 5.0 to 9.0, AI—antibodies index, and SD—standard deviation.