Table 1.
Odds ratios (OR) and 95% confidence intervals (CI) for associations between dust components and allergic conditions, NHANES 2005–2006 (N = 5409).
| Dust Allergens | Current Asthma | Wheeze in Past 12 Months | Allergies in Past 12 Months | Allergic Rhinitis in Past 12 Months | ||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | P | |
| Mildew or musty smell | 1.67 (1.10, 2.53) | 0.02 | 1.19 (0.84, 1.68) | 0.31 | 1.68 (1.29, 2.20) | 0.00 | 1.55 (1.16, 2.06) | 0.00 |
| Cockroaches in house | 0.51 (0.40, 0.65) | <0.001 | 0.87 (0.57, 1.32) | 0.49 | 1.03 (0.74, 1.43) | 0.84 | 0.76 (0.48, 1.22) | 0.23 |
| Dog in house | 0.76 (0.47, 1.24) | 0.25 | 0.92 (0.72, 1.18) | 0.49 | 0.82 (0.51, 1.34) | 0.41 | 1.04 (0.67, 1.61) | 0.86 |
| Cat in house | 1.08 (0.80, 1.47) | 0.58 | 1.15 (1.00, 1.33) | 0.05 | 1.12 (0.93, 1.35) | 0.23 | 1.08 (0.90, 1.29) | 0.40 |
| Furry pet in house | 1.00 (0.81, 1.24) | 0.98 | 1.02 (0.81, 1.28) | 0.86 | 1.11 (1.00, 1.24) | 0.05 | 1.18 (0.99, 1.41) | 0.07 |
| Aspergillus fumigatus | 0.85 (0.54, 1.34) | 0.46 | 1.03 (0.73, 1.21) | 0.87 | 0.99 (0.70, 1.42) | 0.98 | 1.32 (0.74, 1.73) | 0.54 |
| Bla g 1 | 1.21 (0.82, 1.77) | 0.31 | 1.08 (0.81, 1.44) | 0.57 | 1.04 (0.83, 1.29) | 0.75 | 1.26 (0.91, 1.76) | 0.15 |
| Bla g 2 | 0.75 (0.47, 1.19) | 0.20 | 0.95 (0.74, 1.21) | 0.64 | 0.99 (0.69, 1.43) | 0.97 | 0.91 (0.73, 1.14) | 0.40 |
| Can f 1 | 1.90 (0.93, 3.86) | 0.07 | 1.43 (0.95, 2.47) | 0.08 | 1.31 (0.55, 3.11) | 0.52 | 1.67 (1.07, 2.63) | 0.02 |
| Der f 1 | 0.63 (0.38, 1.05) | 0.07 | 0.70 (0.48, 1.04) | 0.08 | 0.72 (0.55, 0.95) | 0.02 | 0.76 (0.57, 1.01) | 0.05 |
| Der p 1 | 1.36 (0.81, 2.28) | 0.23 | 1.21 (0.85, 1.73) | 0.27 | 0.91 (0.63, 1.31) | 0.59 | 0.89 (0.62, 1.29) | 0.53 |
| Fel d 1 | 1.37 (0.80, 2.35) | 0.23 | 1.30 (0.64, 2.64) | 0.44 | 1.55 (0.92, 2.61) | 0.10 | 0.94 (0.57, 1.56) | 0.80 |
| Mus m 1 | 0.88 (0.52, 1.51) | 0.63 | 0.91 (0.53, 1.59) | 0.73 | 0.87 (0.64, 1.20) | 0.38 | 0.87 (0.58, 1.31) | 0.48 |
| Rat n 1 | 1.35 (0.91, 1.99) | 0.13 | 1.07 (0.77, 1.50) | 0.66 | 0.96 (0.68, 1.35) | 0.80 | 1.00 (0.77, 1.29) | 0.97 |
| Endotoxin | 1.44 (1.05, 1.99) | 0.02 | 1.39 (0.94, 2.06) | 0.10 | 1.15 (0.77, 1.71) | 0.48 | 1.06 (0.66, 1.71) | 0.79 |
Abbreviations: OR, odds ratio; CI, confidence interval; Bla g, Blattella germanica; Can f, Canis familiaris; Der f, Dermatophagoides farinae; Der p, Dermatophagoides pteronyssinus; Fel d, Felis domesticus; Mus m, mouse urinary protein; Rat n, rat urinary protein. Odds ratios (OR) calculated using logistic regression analyses adjusting for age, gender, race/ethnicity, family income to poverty ratio, environmental tobacco smoke, BMI, pets’ avoidance or removal, and potential confounding dust allergens. OR estimated for an increase in exposure from lowest to highest quartile of dust allergens concentrations (Aspergillus fumigatus, Bla g1 and 2, Can f1, Fel d1, Der p1, Der f1, Mus m1, Rat n1, endotoxin). Significant results are underlined.