Table 2.
Associations between MCT4 expression and clinicopathological variables in 558 surgically resected patients with gastric adenocarcinoma.
| Variable | MCT4 | Total | p-Value | ||
|---|---|---|---|---|---|
| Low | High | ||||
| Year of surgery | |||||
| ≥2000 | 100 (34.5%) | 148 (55.2%) | 248/558 | 0.000 | |
| <2000 | 190 (65.5%) | 120 (44.8%) | 310/558 | ||
| Age | |||||
| <69 | 152 (52.4%) | 129 (48.1%) | 281/558 | 0.351 | |
| ≥69 | 138 (47.6%) | 139 (51.9%) | 277/558 | ||
| Sex | |||||
| Male | 173 (59.7%) | 168 (62.7%) | 341/558 | 0.487 | |
| Female | 117 (40.3%) | 100 (37.3%) | 217/558 | ||
| T | |||||
| T1 + 2 | 96 (33.1%) | 68 (25.4%) | 164/558 | 0.051 | |
| T3 + 4 | 194 (66.9%) | 200 (74.6%) | 394/558 | ||
| Lymph nodes | |||||
| negative | 169 (58.3%) | 124 (46.3%) | 293/558 | 0.005 | |
| positive | 121 (41.7%) | 144 (53.7%) | 265/558 | ||
| Organ metastases | |||||
| negative | 273 (94.1%) | 252 (94.0%) | 525/558 | 1.000 | |
| positive | 17 (5.9%) | 16 (6.0%) | 33/558 | ||
| Stage | |||||
| I + II | 180 (62.1%) | 159 (59.3%) | 339/558 | 0.282 | |
| III + IV | 110 (37.9%) | 109 (40.7%) | 219/558 | ||
| Histological grade in intestinal type | |||||
| I | 80 (66.7%) | 96 (58.9%) | 176/283 | 0.215 | |
| II + III | 40 (33.3%) | 67 (41.1%) | 107/283 | ||
| Lauren | |||||
| Intestinal | 120 (41.4%) | 163 (60.8%) | 283/558 | 0.000 | |
| Diffuse | 159 (54.8%) | 97 (36.2%) | 256/558 | ||
| Other * | 11 (3.8%) | 8 (3.0%) | 19/558 | ||
| Perioperative chemotherapy | |||||
| Yes | 5 (1.7%) | 17 (6.3%) | 22/558 | 0.008 | |
| No | 285 (98.3%) | 251 (93.7%) | 536/558 | ||
| Radicality of resection | |||||
| R0 | 212 (73.1%) | 202 (75.4%) | 0.562 | ||
| R1 or R2 | 78 (26.9%) | 66 (24.6%) | |||
Other *: mixed, no classified; Statistically significant values are bolded.