Table 3.
Associations between MTCO1 expression and clinicopathological variables in 562 surgically resected patients with gastric adenocarcinoma.
| Variable | MTCO1 | Total | p-Value | ||
|---|---|---|---|---|---|
| Low | High | ||||
| Year of surgery | |||||
| ≥2000 | 149 (49.8%) | 99 (37.6%) | 248/562 | 0.004 | |
| <2000 | 150 (50.2%) | 164 (62.4%) | 314/562 | ||
| Age | |||||
| <69 | 153 (51.2%) | 131 (49.8%) | 284/562 | 0.800 | |
| ≥69 | 146 (48.8%) | 132 (50.2%) | 278/562 | ||
| Sex | |||||
| Male | 173 (57.9%) | 169 (64.3%) | 342/562 | 0.141 | |
| Female | 126 (42.1%) | 94 (35.7%) | 220/562 | ||
| T | |||||
| T1 + 2 | 94 (31.4%) | 74 (28.1%) | 168/562 | 0.407 | |
| T3 + 4 | 205 (68.6%) | 189 (71.9%) | 394/562 | ||
| Lymph nodes | |||||
| negative | 160 (53.5%) | 136 (51.7%) | 296/562 | 0.673 | |
| positive | 139 (46.5%) | 127 (48.3%) | 266/562 | ||
| Organ metastases | |||||
| negative | 275 (92.0%) | 254 (96.6%) | 529/562 | 0.030 | |
| positive | 24 (8.0%) | 9 (3.4%) | 33/562 | ||
| Stage | |||||
| I + II | 179 (59.9%) | 164 (62.4%) | 343/562 | 0.603 | |
| III + IV | 120 (40.1%) | 99 (37.6%) | 219/562 | ||
| Histological grade in intestinal type | |||||
| I | 83 (60.1%) | 95 (64.6%) | 178/285 | 0.464 | |
| II + III | 55 (39.9%) | 52 (35.4%) | 107/285 | ||
| Lauren | |||||
| Intestinal | 138 (46.2%) | 147 (55.9%) | 285/562 | 0.044 | |
| Diffuse | 148 (49.5%) | 110 (41.8%) | 258/562 | ||
| Other * | 13 (4.3%) | 6 (2.3%) | 19/562 | ||
| Perioperative chemotherapy | |||||
| Yes | 15 (5.0%) | 6 (2.3%) | 541/562 | 0.118 | |
| No | 284 (95.0%) | 257 (97.7%) | 21/562 | ||
| Radicality of resection | |||||
| R0 | 219 (73.2%) | 199 (75.7%) | 418/562 | 0.288 | |
| R1 or R2 | 80 (26.8%) | 64 (24.3%) | 144/562 | ||
Other *: mixed, no classified; Statistically significant values are bolded.