ADP |
Adenosine diphosphate |
AGT |
O(6)-alkylguanine-DNA alkyltransferase |
AKT |
Protein kinase B |
AMPK |
AMP-activated protein kinase |
APC |
Antigen presenting cell |
ARG1 |
Arginase 1 |
ASK1 |
Activation of apoptosis signal regulating kinase |
BCL2 |
B-cell lymphoma 2 |
BH4
|
Tetrahydrobiopterin |
CAFs |
Cancer-associated fibroblasts |
CAV1 |
Caveolin-1 |
CDK5 |
Cyclin-dependent kinase 5 |
cGMP |
Cyclic guanosine monophosphate |
Cys |
Cysteine |
DETA-NO |
Diethylenetriamine/nitric oxide |
ECM |
Extracellular matrix |
eNOS/NOS3 |
Endothelial NOS |
ERK |
Extracellular signal-regulated Kinase |
ETC |
Electron transport chain |
ETS1 |
ETS Proto-Oncogene 1 |
FAK1 |
Focal adhesion kinase |
FOXO1 |
Forkhead Box O1 |
GAPDH |
Glyceraldehyde 3-phosphate dehydrogenase |
G-CSF |
Granulocyte-colony-stimulating factor |
M-CSF |
Macrophage-colony-stimulating factor |
GLUT1 |
Glucose transporter 1 |
GSH |
Gluthatione |
GSNO |
S-Nitrosoglutathione |
GSNOR |
Glyceryl trinitrate |
GTN |
Guanosine-5′-triphosphate |
GTP |
S-Nitrosoglutathione reductase |
H2O2
|
Hydrogen peroxide |
HCC |
Hepatocellular carcinoma |
HHcy |
Hyperhomocysteinemia |
HGF |
Hepatocyte growth factor |
HIF1-α |
Hypoxia-inducible factor 1α |
HNSCC |
Head and neck squamous cell carcinoma |
IFNγ |
Interferon gamma |
IL-2 |
Interleukin-2 |
iNOS/NOS2 |
Inducible NOS |
IκB |
Inhibitor of NF-κB |
IKKβ |
IκB kinase |
L-NAME |
L-NG-Nitro arginine methyl ester |
L-NMMA |
NG-Monomethyl-L-Arginine |
LTBP1 |
Latent TGF-β binding protein |
MAPK |
Mitogen-activated protein kinases |
MDSCs |
Myeloid-derived suppressor cells |
MHC I |
Major histocompatibility complex I |
MMP2/9 |
Matrix metalloproteinase-2/-9 |
mtNOS |
Mitochondrial NOS |
MTOC |
Microtubule-organizing center |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
NF-κB |
Nuclear factor kappa B |
NK cells |
Natural killer cells |
nNOS/NOS1 |
Neuronal NOS |
NO |
Nitric oxide |
NOS |
Nitric oxide synthase |
NSAID |
Non-steroidal anti-inflammatory drugs |
NSCLC |
Non-small cell lung carcinoma |
ODD |
Oxygen-dependent degradation domain |
PARP |
poly [adenosine diphosphate (ADP-ribose)] polymerase |
PDAC |
Pancreatic ductal adenocarcinoma |
PKG |
cGMP-dependent protein kinase |
PRDX2 |
Peroxiredoxin-2 |
PTM |
Post-translational modification |
PTPS |
6-pyruvoyl-tetrahydropterin synthase |
RNS |
Reactive nitrogen species |
sGC |
Soluble gualylyl cyclase |
SNO |
S-nitrosotyiol |
SIRT1 |
Sirtuin 1 |
STAT3 |
Signal transducer and activator of transcription 3 |
SNAP |
S-nitroso-N-acetylpenicillamine |
SNO |
S-nitrosothiols |
TAMs |
Tumor-associated macrophages |
TCA cycle |
Tricarboxylic acid cycle |
TCR |
T cell receptor |
TG2 |
Transglutaminase 2 |
TGF-β |
Transforming growth factor beta |
Th1 |
T helper 1 |
Th2 |
T helper 2 |
TIE2 |
TEK tyrosine kinase |
TLR |
Toll-like receptor |
TNBC |
Triple-negative breast cancer |
TNF |
Tumor necrosis factor |
Trx |
Thioredoxin |
Trx/R |
Thioredoxin reductase |
TME |
Tumor micro-environment |
TRAP1 |
TNF receptor associated protein 1 |
TWIST1 |
Twist-related protein 1 |
VEGF |
Vascular endothelial growth factor |