Table 5.

Overview of the properties of relevant therapeutic radionuclides [65]. N/A, not available.

Radionuclide	Total Energy Emitted Per Decay (MeV)	Preclinical Activity Injected in Mouse Model *	Relevant Clinical Doses
212Pb (t1/2 = 10.6 h)	7.90 (1 α, 2 β)	0.3 MBq	60–80 MBq **
177Lu (t1/2 = 6.7 days)	0.15 (1 β)	30 MBq	6–8 GBq [6]
225Ac (t1/2 = 10.0 days)	27.90 (4 α, 2 β)	30 kBq	6–8 MBq [12,13,14]
213Bi (t1/2 = 45.6 min)	8.47 (1 α, 2 β)	N/A	296 MBq [17]

* Activity dose that result in TIs of around 2–3 (compared to control), ** calculated from a factor of 200–267 compared to mice, corresponding to mouse–human factor of 200–267 for ¹⁷⁷Lu and ²²⁵Ac.