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The core analysis of top canonical pathways. The core analysis of the 8 overlapping molecules (JUN, MAPK3, MMP9, IL6, IL1B, TNF, IL1, and IFG1R) identified a series of canonical pathways associated with the molecules, which are listed in order of decreasing –log(B-H p-value). The dark highlighted pathways, neuroinflammation signaling pathways, and HGMB1 signaling, were the ones chosen for further investigation of their role in Alzheimer’s disease.
