Table 2.
Ridge regression analysis for OS per list of immune-evasive genes.
| Categories of Immune Evasion | p Value Discovery | p Value Validation | ||||
|---|---|---|---|---|---|---|
| Multivariate | Multivariate Holm | Passed | Multivariate | Multivariate Holm | Passed | |
| Antigen presentation (n = 14) | 0.92 × 10−3 | 9.20 × 10−4 | Yes | 1.50 × 10−1 | 1.50 × 10−1 | No |
| Immune cells (n = 1) | 2.78 × 10−7 | 5.57 × 10−7 | Yes | 6.00 × 10−2 | 1.20 × 10−1 | No |
| Cell death (n = 51) | 3.85 × 10−20 | 2.31 × 10−19 | Yes | 2.73 × 10−7 | 1.92 × 10−6 | Yes |
| Immune checkpoints (n = 9) | 1.27 × 10−9 | 3.81 × 10−9 | Yes | 2.76 × 10−7 | 1.92 × 10−6 | Yes |
| Metabolic checkpoints (n = 77) | 1.02 × 10−20 | 7.19 × 10−20 | Yes | 4.46 × 10−6 | 2.23 × 10−5 | Yes |
| Oncogenic signaling pathways (n = 38) | 4.18 × 10−16 | 2.09 × 10−15 | Yes | 1.71 × 10−5 | 6.23 × 10−5 | Yes |
| TME (n = 20) | 1.22 × 10−15 | 4.91 × 10−15 | Yes | 1.53 × 10−5 | 6.22 × 10−5 | Yes |