Table 1.
Demographic data and prevalence of mental disorders among the offspring of parents with or without IBS.
| Demographic Characteristics | Parents with IBS and Their Children (n = 8377) | Parents without IBS and Their Children (n = 33,508) | p |
|---|---|---|---|
| Age of parents (years, SD) | 56.92 (11.62) | 56.91 (11.63) | 0.931 |
| Sex of parents (n, %) | 1.000 | ||
| Male (father) | 4108 (49.0) | 16,432 (18.0) | |
| Female (mother) | 4269 (51.0) | 17,076 (51.0) | |
| Age of children (years, SD) | 28.58 (11.92) | 28.59 (11.91) | 0.942 |
| Sex of children (n, %) | 0.883 | ||
| Male (son) | 4560 (54.4) | 18,208 (54.3) | |
| Female (daughter) | 3817 (45.6) | 15,300 (45.7) | |
| Mental disorders of parents (n, %) | |||
| Schizophrenia | 52 (0.6) | 129 (0.4) | 0.004 |
| Bipolar disorder | 72 (0.9) | 123 (0.4) | <0.001 |
| Major depressive disorder | 360 (4.3) | 468 (1.4) | <0.001 |
| IBS of children (n, %) | 312 (3.7) | 536 (1.6) | <0.001 |
| Mental disorders of children (n, %) | |||
| ADHD | 134 (1.6) | 397 (1.2) | 0.003 |
| ASD | 19 (0.2) | 62 (0.2) | 0.412 |
| Schizophrenia | 54 (0.6) | 207 (0.6) | 0.762 |
| Bipolar disorder | 32 (0.4) | 105 (0.3) | 0.337 |
| Major depressive disorder | 94 (1.1) | 270 (0.8) | 0.006 |
| Level of urbanization (n, %) | 1.000 | ||
| 1 (most urbanized) | 1876 (22.4) | 7504 (22.4) | |
| 2 | 3012 (36.0) | 12,048 (36.0) | |
| 3 | 1022 (12.2) | 4088 (12.2) | |
| 4 | 826 (9.9) | 3304 (9.9) | |
| 5 (most rural) | 1641 (19.6) | 6564 (19.6) | |
| Income-related insured amount | 1.000 | ||
| ≤15,840 NTD/month | 3288 (39.3) | 13,152 (39.3) | |
| 15,841~25,000 NTD/month | 2381 (28.4) | 9524 (28.4) | |
| ≥25,001 NTD/month | 2708 (32.3) | 10,832 (32.3) |
ADHD attention deficit hyperactivity disorder; ASD autism spectrum disorder; IBS irritable bowel syn-drome; SD standard deviation; Bold type indicates the statistical significance.