TP53 |
Tumor protein p53 |
CDKN2A |
Cyclin-dependent kinase inhibitor 2A |
KRAS |
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
MRI |
Magnetic resonance imaging |
CT |
Computerized tomography |
CA199 |
Carbohydrate antigen 199 |
PC |
Pancreatic cancer |
CA125 |
Cancer antigen 125 |
GEM |
Gemcitabine |
CEA |
Carcinoembryonic antigen |
CA50 |
Carbohydrate antigen 50 |
CP |
Chronic pancreatitis |
AP |
Acute pancreatitis |
RECIST |
response evaluation criteria in solid tumors |
SPINK1 |
Serine protease inhibitor Kazal-type 1 |
PSCs |
Pancreatic stellate cells |
SST1 |
symbiotic sulfate transporter 1 |
MCP-1 |
Monocyte chemoattractant protein-1 |
Hic-5 |
Hydrogen peroxide-inducible clone-5 |
PDAC |
Pancreatic ductal adenocarcinoma |
CXCR2 |
C-X-C motif chemokine receptor 2 |
ACSL3 |
Long-chain acyl coenzyme A synthase 3 |
ADAM10 |
A Disintegrin and metalloproteinase domain-containing protein 10 |
CAFs |
Cancer-related fibroblasts |
FN |
Fibronectin |
SMO |
Smoothened |
FGFR |
Fibroblast growth factor receptor |
Hh |
Hedgehog |
ER stress |
Endoplasmic reticulum stress |
CAV1 |
Caveolin-1 |
ACTA2 |
Actin alpha 2 |
Tregs |
Regulatory T cells |
MDSCs |
Myeloid-derived suppressor cells |
myCAFs |
Myofibroblastic CAFs |
iCAFs |
Inflammatory CAFs |
apCAFs |
Antigen-presenting CAFs |
NK cells |
Natural killer cells |
CDH11 |
Cadherin 11 |
SMAD4 |
SMAD family member 4 |
TME |
Tumor microenvironment |
NDRG1 |
N-myc downstream regulated gene-1 |
CM |
Camostat mesilate |
HIF-1α |
Hypoxia-inducible factor 1 alpha |
MIR |
MicroRNA |
ECM |
Extracellular matrix |
NFs |
Normal fibroblasts |
MEFs |
Mouse embryonic fibroblasts |
IL-6 |
Interleukin-6 |
IL-8 |
Interleukin-8 |
IL-1α |
Interleukin-1 alpha |
IL-1β |
Interleukin 1 beta |
TCR |
T cell antigen receptor |
NET-G1 |
Grade 1 neuroendocrine tumor |
4E-BP1 |
Eukaryotic translation initiation factor 4E binding protein 1 |
MHC II |
Major histocompatibility complex II |
ROS |
Reactive oxidative species |
Nrf2 |
Nuclear factor erythroid 2–related factor 2 |
NUPR1 |
Nuclear protein 1 |
NAC |
N-acetyl cysteine |
SOD |
Superoxide dismutase |
CoQ10 |
Coenzyme Q10 |