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. 2021 Apr 30;22(9):4763. doi: 10.3390/ijms22094763
ADR Adriamycin
APIs Active pharmaceutical ingredient
AML Acute myeloid leukemia
AMPK 5′ Adenosine monophosphate-activated protein kinase
APIs Active pharmaceutical ingredients
BW Body weight
BBB Blood–brain barrier
CAM Camphor
CAP Capric acid
CV Carvacrol
CVN Carvone
CoN Colon epithelial cells
COX-2 Cyclooxygenase-2
cSLNs Cationic solid lipid nanoparticles
DEN Diethylnitrosamine
DESs Deep eutectic solvents
DMBA 7,12-Dimethylbenz[a]anthracene
DMH 1,2-Dimethylhydrazine
EC50 Effective concentration of a drug or concentration of a drug which is calculated to inhibit virus induced cell death by 50%
ERK Extracellular signal-regulated kinases
EU Eucalyptol
GBA Glioblastoma
GI50 The 50% growth inhibition percentage
GI% The cell growth inhibition percentage values
HBAs Hydrogen bond acceptors
HC Hepatocellular carcinoma
HDFs Human dermal fibroblasts
HRPC Hormone-refractory prostate cancer
IBU Ibuprofen
IC50 Concentration of an inhibitor where the response (or binding) is reduced by half
LIM limonene
LIM-SLNs Solid lipid nanoparticles formulation with (+)-limonene 1,2-epoxide and glycerol monostearate
LPO Lipid peroxidation
MAPK Mitogen-activated protein kinase
MA Myristic acid
ME Menthol
MTT 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
MTT assay The colorimetric assay based on the reduction of yellow tetrazolium salt (MTT) to purple formazan
NADESs Natural deep eutectic systems
NEO100 Highly pure perillyl alcohol
NR 3-Amino-7-dimethyl-2-methylphenazine hydrochloride
NR assay The neutral red (NR) dye uptake assay
NEO212 Compound built of perillyl alcohol and temozolomide
p21waf1 Cyclin-dependent kinase inhibitor
PAH Perillaldehyde
3-PCA Pyrrolidine-3-carboxylic acid
PE Perillaldehyde 1,2-epoxide
PLK1 Polo-like kinase 1
PM Physical mixtures
POH Perillyl alcohol
ROS Reactive oxygen species
SLNs Solid lipid nanoparticles
SRB Sulforhodamine B
SAR Structure-activity relationship
THEDES Therapeutic deep eutectic system
THEDESs Therapeutic deep eutectic solvents
TMZ Temozolomide
TRPM8 Transient receptor potential melastatin member 8