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. 2021 Apr 30;26(9):2630. doi: 10.3390/molecules26092630

Figure 5.

Figure 5

Effect of OXY on the gene expression of pro-inflammatory cytokines and enzymes (n = 8/group). The mRNA expression levels of pro-inflammatory cytokines and enzymes were determined via quantitative real-time polymerase chain reaction (qPCR) (A‒F). NC, normal control group; model, DSS-induced colitis model group; DSS + OXY-2.5, DSS-induced colitis rats treated with OXY (2.5 mg/kg) group; DSS + OXY-5, DSS-induced colitis rats treated with OXY (5 mg/kg) group; OXY-5, rats treated with OXY (5 mg/kg) alone group. The values are expressed as mean ± SEM. Significant differences among groups were evaluated via ANOVA with Tukey’s post hoc HSD. ** p < 0.01 and *** p < 0.001 compared with the NC group; # p < 0.05, ## p < 0.01, and ### p < 0.001 compared with the model group.