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. 2021 Apr 29;10(9):1929. doi: 10.3390/jcm10091929

Table 4.

Unadjusted and adjusted odds ratios for the development of diabetic nephropathy in patients equal to or more than 65 years old and less than 65 years old.

Hypertension Status Model 1 * Model 2 * Model 3
Unadjusted OR (95%CI) p Value Adjusted OR (95%CI) p Value Adjusted OR (95%CI) p Value
≥65 years old
Normal HBP group 1 1 1
Isolated high HSBP group 1.90 (0.85–4.23) 0.116 1.70 (0.67–4.33) 0.263 1.68 (0.66–4.27) 0.275
<65 years old
Normal HBP group 1 1 1
Isolated high HSBP group 3.08 (0.76–12.5) 0.116 3.07 (0.62–15.1) 0.167 3.06 (0.63–15.0) 0.167

HBP, home blood pressure; HSBP, home systolic blood pressure; * Model 2: Odds ratios were adjusted for sex, age, duration of diabetes mellitus, body mass index, hemoglobin A1C, total cholesterol, creatinine, and the use of antihypertensive medications. * Model 3: Odds ratios were adjusted for variables in Model 2 and additional adjustment for the use of renin–angiotensin system inhibitors instead of the use of antihypertensive medications.