Table 5.
Unadjusted and adjusted odds ratios for the development of diabetic nephropathy in patients according to systolic blood pressure.
| Hypertension Status | Model 1 | * Model 2 | * Model 3 | |||
|---|---|---|---|---|---|---|
| Unadjusted OR (95%CI) | p Value | Adjusted OR (95%CI) | p Value | Adjusted OR (95%CI) | p Value | |
| ≥135 mmHg | ||||||
| Normal HBP group | 1 | 1 | 1 | |||
| Isolated high HSBP group | 4.21 (1.73–12.6) | 0.0009 | 5.59 (2.02–19.1) | 0.0005 | 5.39 (1.92–18.6) | 0.0008 |
| <135 mmHg | ||||||
| Normal HBP group | 1 | 1 | 1 | |||
| Isolated high HSBP group | 1.31 (0.63–2.52) | 0.452 | 0.75 (0.33–1.57) | 0.449 | 0.71 (0.32–1.35) | 0.384 |
HBP, home blood pressure; HSBP, home systolic blood pressure; * Model 2: Odds ratios were adjusted for sex, age, duration of diabetes mellitus, body mass index, hemoglobin A1C, total cholesterol, creatinine, and the use of antihypertensive medications. * Model 3: Odds ratios were adjusted for variables in Model 2 and additional adjustment for the use of renin–angiotensin system inhibitors instead of use of antihypertensive medications.