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. 2021 Apr 28;22(9):4614. doi: 10.3390/ijms22094614

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Antacid effects of TA-CaCO₃ using the colorimetric bromothymol blue (BTB) method. (a) Color changes and (b) UV/vis spectra of BTB under PBS (pH = 7.4) and simulated gastric fluid (SGF, pH = 1.5) after treatment with commercial CaCO₃ and 1:75 TA-CaCO₃. Green-colored arrows indicate a pH increase.