Table 3.
Subfamily | PDB ID | Function | References |
---|---|---|---|
ABCB1 (P-gp) | 4F4C, 4M1M, 4M2S, 4M2T, 4Q9H, 4Q9J, 4Q9K, 4Q9L, 4XWK, 5KPF, 6KPI, 5KPJ, 5KO2, 5KOY, 6C0V, 6GDI, 6Q81, 6QEX, 6QEE, 6FN4, 6FN1, 3G5U, 3G60, 3G61 | Multidrug export, detoxification | [255,296,302,303,304,305,306,308,309,310] |
ABCC1 (MRP1) | 5UJA, 5UJ9, 6BHU, 6UY0 | Multidrug, leukotriene and sphingolipid export, detoxification | [298,312] |
ABCG2 (BCRP) | 5NJG, 5NJ3, 6ETI, 6FEQ, 6HIJ, 6HCO, 6HBU, 6HZM, 6VXH, 6VXI, 6VXJ | Multidrug export, detoxification and urate transport | [256,257,258,259] |