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. 2021 Apr 30;22(9):4806. doi: 10.3390/ijms22094806

Table 3.

Atomic structures of eukaryotic MDR ABC transporters.

Subfamily PDB ID Function References
ABCB1 (P-gp) 4F4C, 4M1M, 4M2S, 4M2T, 4Q9H, 4Q9J, 4Q9K, 4Q9L, 4XWK, 5KPF, 6KPI, 5KPJ, 5KO2, 5KOY, 6C0V, 6GDI, 6Q81, 6QEX, 6QEE, 6FN4, 6FN1, 3G5U, 3G60, 3G61 Multidrug export, detoxification [255,296,302,303,304,305,306,308,309,310]
ABCC1 (MRP1) 5UJA, 5UJ9, 6BHU, 6UY0 Multidrug, leukotriene and sphingolipid export, detoxification [298,312]
ABCG2 (BCRP) 5NJG, 5NJ3, 6ETI, 6FEQ, 6HIJ, 6HCO, 6HBU, 6HZM, 6VXH, 6VXI, 6VXJ Multidrug export, detoxification and urate transport [256,257,258,259]