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. 2021 May 6;13(9):2224. doi: 10.3390/cancers13092224

Table 3.

Toxicities with TKI treatment.

Events No. of Adverse Events
Total Grade 1 Grade 2 Grade 3 Grade 4
Asthenia 14 13 (93%) 1 (7%) 0 0
Edema 9 9 (100%) 0 0 0
Nausea/vomiting/anorexia 9 6 (67%) 1 (11%) 2 (22%) 0
Diarrhea 4 3 (75%) 1 (25%) 0 0
Abdominal pain 3 3 (100%) 0 0 0
Gastroesophageal reflux 1 1 (100%) 0 0 0
Toxidermia 5 4 (80%) 1 (20%) 0 0
Aphthous stomatitis 1 1 (100%) 0 0 0
Thrombocytopenia 1 1 (100%) 0 0 0
Neutropenia 2 0 0 1 (50%) 1 (50%)
Myalgias 2 2 (100%) 0 0 0
Elevated liver enzymes 1 1 (100%) 0 0 0
Cholestasis 1 0 0 1 (100%) 0
Tachycardia 1 1 (100%) 0 0 0
Amnesia 1 1 (100%) 0 0 0
CPK increased 1 0 1 (100%) 0 0