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PD173074 inhibitor prevents FGF2-induced transcription of MLL-AF4 target genes. Graphs show transcript levels of MLL-AF4 target genes in leukemia cells, RS4;11 (left) and in SEM (right), stimulated with FGF2 (FGF) or pretreated with PD173074 (FGF + PD). Cells treated with DMSO (vehicle) are used as a control (CTRL); R.U., relative units; p-values are indicated as follows: * p < 0.05, *** p < 0.005.
