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Performance of optimal 6-miRNA biomarker panel.
| Performance Characteristic | High Specificity Biomarker Score Cut-Off |
High Sensitivity Biomarker Score Cut-Off |
|---|---|---|
| Sensitivity | 41.1% (35.2%–47.2%) | 79.5% (74.0%–84.0%) |
| Specificity | 89.8% (85.4%–93.1%) | 62.2% (56.1%–68.0%) |
| PPV | 60.0% (53.9%–65.9%) | 43.9% (38.0%–50.1%) |
| NPV | 80.4% (75.0%–84.9%) | 89.1% (84.5%–92.5%) |
