Skip to main content
. 2021 Apr 27;22(9):4606. doi: 10.3390/ijms22094606

Figure 3.

Figure 3

Figure 3

pCTX-M3 family plasmids. (a) Alignment of pCTX-M3 and related plasmids; (b) Alignment of diverse multiple resistance regions. The ORFs are represented as arrows, rep genes are in black, drug resistance genes in red, mercury-resistance operon in pink, ferric citrate transport genes in pale blue, conjugative transfer genes in green, transposase genes in yellow (IS26 transposase genes are outlined in green in panel b), integron integrase-encoding genes in violet, parAB and pemIK in blue, mucA and mucB in grey, and others in white. Plasmid nucleotide sequences were taken from GenBank at following accession numbers: pC15_002—CP042490, pOXAPSS2—KU159086, pCTXM360—EU938349, pCTX-M3—AF550415, pSEIL-3—MN380440, pNDM-HK—HQ451074, pNDM-OM—JX988621, pCEX18—LC556221, pCEX24—LC556214, pCEX6—LC556219, p1_FDAARGOS_1327—CP069833, p2_AKB48—CP044337, p2_KP38371—CP014298, pA1-3—LC508263, pB12AN_1—CP026156, pC9_002—CP042532, pE51_003—CP042537, pC2_002—CP042522, pE5_003—CP042574, pC16_002—CP042580, pE1_004—CP042509, pE11_002—CP042526, pEC41—MW548582, pEl1573—JX101693, pEa1631—MG516907, pEsST2350_SE_NDM—CP031322, pEsST410_NW_NDM—CP031235, pEsST80_L1_NDM—CP031216, pKOCBH-C—CP035217, pLM6771—KX009507, pWP5-S18-CRE-01_2—AP022128, pIMP_HB623—KM877517, pIT-Cfr_01/2015—MH722216, pIT-Kpn_01/2014—MH722217, pIT-Sma_01/2014—MH722219, pl. 2 of S. enterica subsp. enterica serovar Senftenberg AR_0127—CP032193, RCS55_pl—LT985387, RCS40_pl—LT985241, and plasmid 6 K. pneumoniae—LT968692. All sequences were rotated or inverted and rotated to begin with repC. Plasmid schemes are drawn to scale. Original annotations are used. Color dots in front of the plasmid name denote the source of bacteria from which the plasmid was isolated: red—humans, orange—farm animals, yellow—wildlife, blue—humans or animals, and purple—wastewater. Sequence homology is color-coded according to scale below the alignment.