TABLE 1.
Summary of differentially expressed transcripts and proteins following HHQ exposurea
| HHQ concn (ng/ml) | No. of transcripts or proteins |
|||||
|---|---|---|---|---|---|---|
| 24 h |
72 h |
|||||
| Upregulated | Downregulated | Unchanged | Upregulated | Downregulated | Unchanged | |
| Transcripts | ||||||
| 1 | 13 | 20 | 31,476 | 0 | 0 | 31,549 |
| 10 | 2,702 | 1,990 | 26,817 | 382 | 159 | 31,008 |
| 100 | 5,948 | 6,605 | 18,956 | 6,166 | 5,698 | 19,685 |
| Proteins | ||||||
| 1 | NA | NA | NA | 0 | 0 | 5,528 |
| 10 | NA | NA | NA | 3 | 0 | 5,525 |
| 100 | NA | NA | NA | 628 | 375 | 4,525 |
a
Expression with each HHQ treatment was compared to expression with the vehicle control (DMSO) treatment (q value of <0.05 by Welch’s approximate t test). NA, not applicable.