FIG 6.

Type III IFN, type I IFN, and IP10 production in HRSV-infected primary well-differentiated airway organoid cultures at ALI. Well-differentiated airway organoid cultures at ALI were infected with either rHRSV^A2EGFP(5), rHRSV^A11EGFP(5), or rHRSV^B05EGFP(5) at a standardized low viral inoculum. Apical washes were taken at 0, 1, 2, and 3 days postinfection (DPI), and type III IFN (IL28A/B, IL-29) (A), type I IFN (IFN-α2 and IFN-β) (B), and IP10 (C) were quantified using the BD LEGENDplex human antivirus response panel. One independent experiment is shown, and all experiments were performed in triplicate. Mean and standard deviation are shown.