Table 2.

Acute and chronic variations of norepinephrine levels. Data are shown as mean ± standard error of the mean (SEM). Average values of norepinephrine ± SEM are reported at baseline (T0), after the first dTMS session (T1), before (T2), and after the last (15th) dTMS session (T3) for all three groups (HF, high frequency 18 Hz; LF, low frequency 1 Hz; sham). Comparisons at different times (T0 vs. T1, T2 vs. T3, T0 vs. T2) were obtained with two-tailed Student’s t-tests. For all tests, differences were considered statistically significant at p ≤ 0.05. Legend: HF = high frequency; LF = low frequency; * p < 0.05; ** p < 0.01.

	Norepinephrine (ng/mL)
	T0	T1	T0 vs. T1	T2	T3	T2 vs. T3	T0 vs. T2
HF Group	4.7 ± 0.8	5.7 ± 0.7	* 0.046	1.8 ± 0.7	1.7 ± 0.6	0.250	** 0.007
LF Group	4.7 ± 0.9	4.0 ± 1.2	0.261	3.1 ± 0.7	2.2 ± 0.4	0.259	* 0.041
Sham Group	4.2 ± 0.9	3.6 ± 1.4	0.465	3.4 ± 1.5	4.3 ± 1.6	0.578	0.473